RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-199a-2
RNA ID
RNA Type
miRNA
Alteration Pattern
up regulation
Species
mus musculus
Detection Methods
qRT-PCR; dual-luciferase reporter assay etc.
Target
SFRP5
Pathway
NA
PubMed ID
Title
MicroRNA-199a regulates myocardial fibrosis in rats by targeting SFRP5
Year
2019
Function
"Microrna-199a deficiency can inhibit the proliferative and migratory potentials of cardiac fibroblasts, as well as cardiac fibroblast-to-myofibroblast transformation (CMT) by targeting SFRP5, thus exerting the protective effect on myocardial fibrosis."